The Science

Over the past three decades, VOC sponsored researchers have:

  • Identified the gene mutation responsible for ocular albinism type 1 (OA1), an X-linked recessive disorder in which the retinal pigment epithelium lacks pigment, while the hair and skin appear normal.

  • Developed the first genetic test for OA, allowing for prenatal diagnosis and carrier screening.

  • Created an OA1 mouse model with many characteristics similar to those in human OA1.

  • Determined the biochemical features of the OA1 protein and its involvement in melanogenesis (the production of melanin, which gives color to skin, hair and the iris).

  • Studied the use of stem cells to regenerate damaged eye tissue in mice.

  • Demonstrated the efficacy of gene therapy for inherited eye diseases.

 

19+

Million Children have vision impairments

According to the World Health Organization, an estimated 19 million children face vision impairments.

 

30+

Years funding research

The Vision of Children Foundation is proud to say that we have funded research for over 30 years now. Three decades worth of dedication to finding a cure for genetic vision disorders.

 
 

60+

Percent of cases of childhood blindness are caused by genetic factors

Genes play a highly significant role in eye diseases, some of which are highly prevalent in children and adults.